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Major Research Topics | UKBB DEENFR NotfallSuchbegriffDownloadsMediaPro UKBB Foundation Children's Website referralsEmergency 24hContactTreatment & HospitalisationContact & Site MapAdmission & RegistrationPatients with foreign insuranceDuring the HospitalisationVisiting & Overnight StayCateringEntertainmentCounselling & CareRights & ObligationsDischargeFeedbackEmergencyMedicineMedical TopicsPhysicians & SpecialistsConsulting HoursParental DictionaryDownload CenterCareerJob OffersWorking at the UKBBResidencyFurther EducationResearchResearch at UKBBMajor Research TopicsResearch GroupsPromotion of Young ResearchersAmbulatory Study CenterResearch NetworksThe UKBBPhysicians & SpecialistsDepartments & ServicesMedical ExpertiseOrganisationNewsEventsMediaPro UKBB Foundation Contact & Site MapEmergencyFeedback Currently this content is only misogynist in German.Dieser Inhalt ist momentan nur auf Deutsch verfügbar. Continue / WeiterBack / ZurückNotfall 24h0900 712 712(3.23 CHF / min. from the Swiss landline, possibly likewise 8 Rp. / min. in the waiting loop by network operator)0900 712 713(3.12 CHF / min. for calls from prepaid lamina phones, possibly likewise 8 Rp. / min. in the waiting loop by network operator) Notfallnummern144   Ambulanz145   Bei Vergiftungen117   Polizei118   Feuerwehr Wichtige InformationenSuchbegriffsearchMeistgesuchtBesuchszeitenAnfahrtsplanEintritt/AnmeldungRechte & PflichtenSprechstundeFortbildungFortbildungFortbildungFortbildungFortbildungAnmeldungSie haben bereits ein Konto? E-Mail / Benutzername* Passwort*  Kennwort vergessen  Einloggen Sie sind noch nicht registriert? Jetzt registrierenEmergency Contact 24h0900 712 712 (3.23 CHF / min. from the Swiss landline, possibly likewise 8 Rp. / min. by network operator)   0900 712 713 (3.12 CHF / min. for calls from prepaid lamina phones, possibly likewise 8 Rp. / min. by network operator) Site MapImportant Numbers144   Ambulance145   Tox Center (Poisoning)117   Police118   Fire Department Further InformationKontakt BoxUKBBUniversity Children’s Hospital BaselSpitalstrasse 334056 Basel Switzerland T +41 61 704 12 12 F +41 61 704 12 13 directionsContactVisitreceipt Collection / Reminder  Patient invoice Please contact me Other emptyVisitcancellationFor making an visit or the postponement of an appointment, please contact polyclinic throne office +41 61 704 12 20 Title*Mr.Mrs. First name Last name Phone Email* Please leave blank* Please enter your request  Send Collection / Reminder Collection / Reminder Title*Mr. Mrs. First name* Last name* Phone Email* Please leave blank* Please enter your request  Send Patient invoicePatient invoice Title*Mr. Mrs. First name* Last name* Phone Email* Please leave blank* Please enter your request*  Send Please contact mePlease contact me  TitleMr.Mrs. First name* Last name* Phone number * Email* Who shall contact you?*  How would you like to be contacted? Contact type*phoneemail Message / comment* Spam*  Send OtherOther Title*Mr.Mrs. First name* Last name* Phone Email* Please leave blank* Please enter your request*  send empty  AnredeHerrFrau Nachname* Telefon* E-Mail* Bitte nicht ausfüllen* Ihre Anfrage*  Absenden   HomeResearchMajor Research Topics Major Research TopicsIn developmental pediatrics / pneumology our research focuses on various areas of neonatology, anesthetics, neuropediatrics and pneumology. Our researchers study the minutiae of organ systems in normal children, premature babies, and in children with chronic diseases or developmental delay. Research in hematology / oncology at the UKBB includes diaper leukemia, immune thrombocytopenia and the outcome / late effects of cancer disease and treatment. Experimental research teams in Immunology, and clinical researchers in pediatric infectious diseases and vaccinology, study the minutiae of the thymus gland and lymphoid system, and the outcome and safety of vaccines. Research in pediatric orthopedics focuses on new methods to depict, measure and treat spinal deformities, and to reconstitute unorthodoxy segments without tumor resection. The semester of pediatric neuroorthopedics performs biomechanic wringer and modelling of gait and motor function. Developmental Pediatrics / PneumologyAll research groups in the department of pediatrics and pulmonology and neonatology are closely linked. The research consists of studies on developmental lung and smart-ass physiology in newborns (see moreover the groups of Prof. Sven Schulzke and Dr. Sven Wellmann) and older children with a particular focus on patients who develop wheezing disorders and asthma. They are particularly interested in developing new lung function tests to measure lung function in infants, as well as establishing early inflammatory biomarkers (see moreover the groups of Prof. Urs Frey, Prof. Juerg Hammer, PD Dr. Daniel Trachsel). They study the influence of environmental factors, including air pollution, on lung minutiae and the incubation of asthma (see moreover the groups of Prof. Philipp Latzin, Loretta Müller, PhD). Furthermore, they are involved in several international cohort studies on asthma epidemiology (BILD, SAPALDIA, U-BIOBRED, EFRAIM, CHICOS). Since asthma is a ramified disease, we model chronic asthma and serial lung function as a ramified disease using new mathematical techniques derived from statistical physics (see moreover group Prof. Urs Frey).Flipsideresearch focus in developmental pediatrics is in the zone of neuropediatrics. We study the effect of early morphological or functional lesions of the smart-ass on cognitive minutiae (Prof. Peter Weber, Dr. Alexander Datta) and moreover the pathophysiology and therapy of muscular dystrophy in children (Prof. Dirk Fischer).Research groups Developmental Pediatrics / PneumologyPneumology: Prof. Urs FreyNeonatology: Prof. Sven SchulzkeAnesthetics: Prof. Thomas ErbNeuropediatrics: Prof. Peter Weber Hematology / OncologyResearch in pediatric hematology and oncology focuses on the epidemiology and long-term outcome in pediatric cancer (Prof. Nicolas von der Weid), as well as on epidemiology, clinical and biological aspects of immune thrombocytopenia in children (Prof. Thomas Kühne) and the understanding of the molecular mechanisms underlying vigilant myeloid leukemia (AML) in diaper (Prof. Jürg Schwaller). The research team of Nicolas von der Weid investigates the potential benefits of supervised training in physical worriedness on multiple parameters of cardio-vascular and unorthodoxy health in survivors of paediatric malignancies. The research team of Thomas Kühne has the origin, clinical undertow and management of pediatric immune thrombocytopenia (ITP) as a major focus. His team is moreover responsible for international registries for children and adults with ITP. Nicolas von der Weid, Thomas Kühne and their staff are strongly involved in clinical cancer research as members of the Swiss Pediatric Oncology Group; their main interests are the study of the whole spectrum of paediatric solid tumors and leukemias. The research group of Jürg Schwaller focuses on the molecular biology of diaper AML aiming to identify novel protein kinases involved in the maintenance of leukemic transformation, to write the role of fusion genes associated with poor prognosis AML and to explore the anti-leukemic potential of a series of novel small molecules that interfere with epigenetic regulatory circuits. Research groups Hematology / OncologyOutcome Research in Pediatric Oncology: Prof. Nicolas von der WeidImmune Thrombocytopenia : Prof. Thomas KühnePediatric Leukemia: Prof. Jürg Schwaller Immunology / InfectiologyResearch in pediatric infectious diseases and vaccinology focuses on the epidemiology and prevention of pertussis (Prof. Ulrich Heininger), the diagnosis and prevention of tuberculosis (PD Dr. Nicole Ritz) and the benefit-risk towage of vaccines (PD Dr. Jan Bonhoeffer). The laboratory Pediatric Immunology of Prof. Georg Hollaender investigates the molecular and cellular regulation of thymus minutiae and function. He moreover holds the professorship Developmental Immunology at the University of Oxford. The major research focus in the laboratory molecular medicine in pediatrics (Prof. Daniela Finke) is the minutiae and immune function of innate lymphoid cells in health and disease.Research groups Immunology / InfectiologyPediatric infectious diseases and vaccinology: Prof. Ulrich HeiningerPediatric immunology: Prof. Georg HolländerDevelopmental Immulogy: Prof. Daniela Finke Pediatric Orthopedics In orthopedics, the human biomechanics system dominates diagnostics, indications, therapeutic strategies and rehabilitation. However, untied from instrumented gait analysis, there is a paucity of functional data and thinking. Radiographic towage – the fundamental decision-making and planning tool – is purely static and is by no ways an well-judged reflection of the ramified three-dimensional moving nature of the human locomotor system. It is moreover incapable of providing information on reasoned and ligamentous forces, or muscular response, not to mention the influence of fatigue and environmental conditions on them. The main clinical pediatric and orthopedic units, the department of neuroorthopedics, and spine and tumor surgery move on a worldwide translational research ground to retrieve biomechanics data, and to model the biomechanical reality of children and adolescents with orthopedic diseases. The translation of new insights into novel inobtrusive and surgical therapeutic strategies, planning tools, and implants to provide largest function and modernize the lives of our patients, remains the primary goal. Our research groups are financially supported by the University of Basel, the Department of Surgery of the University of Basel, competitive third party grants (SNF Swiss National Foundation, CTI the Swiss Commission for Technology and Innovation) and several foundations (Arthrosestiftung, Loddenkemper-Stiftung, Stiftung Basler Orthopädie, Stiftung Cerebral, Stiftung Promotio, Robert-Mathys-Foundation, Gebert-Rüf-Stiftung, Paraplegiker-Stiftung). The depiction and simulation of the biomechanical reality – with inclusion of forces, utile shape and properties (e.g. ligamentous stiffness) – in finite element models, and with forward modeling, allows for the computation and simulation of approaches and the comparison with traditional methods. However, these models are time-consuming, not validated and therefore whimsically workable to the individual case. Consequently, we are refining several established and novel options to proceeds in vivo, patient-specific data which can be used directly for the purpose of clinical-decision making or to feed the computer models. In our gait labs at the UKBB, and in Aarau, we measure joint motion, ground reaction forces and dynamic EMG (kinetics and kinematics) with computation of individual muscle forces and function of the legs. A current project in collaboration with the Fachhochschule Bern and the ETH Zurich (Dr. St. Schmid, Dr. S. Lorenzetti) develops a method to also include the spine. Research-wise there is a strong collaboration with the Catholic University of Leuven (Prof. I. Jonkers) and the Politecnico Milano (Prof. C. Frigo). In flipside study, physiologic muscle parameters are assessed in vivo in order to enhance the speed and precision of biomechanical computations in cooperation with the Free University of Amsterdam (H. Haberfelder, Prof. R. Jaspers und Prof. J. Becher). There is an scrutinizingly well-constructed lack of valid in vivo data on the biomechanic properties (stiffness) of spinal segments, although they are fundamental for the minutiae of new operative strategies to prevent unorthodoxy fusion and loss of function in the treatment of severe spinal deformities. Together with the Institute for surgical technology and biomechanics of the University of Bern ISTB (P. Büchler, PhD) we therefore ripened a motorized and programmable measuring device on a hexapod understructure - similar to a flight simulator or a Taylor Spatial Frame - which allows for the intraoperative, uncontrived towage of the relationship between specified forces and the subsequent 3D response of the spinal segment. At a later stage, this invasive study will be linked to the non-invasive spine gait lab project. The tumor group once workaday a finite element and statistical shape model of the pelvis as a understructure for patient-specific implant without tumor resections. The vital biomechanics data (load-deformation policies of the pelvis) were gained by video-analysis of optic markers on the pelvic surface with support of the in-house gait wringer experts. They are used to manufacture patient specific implants in cooperation with an industry partner. Research groups Pediatric OrthopedicsOrthopedics: Prof. Carol HaslerNeuroorthopedics: Prof. Reinald Brunner Related topicsResearch groupsRelated topicsOnly misogynist in German Departments & servicesPhysicians & specialists Head of Research a.i.Prof. Urs Frey, MD, PhD CMO, Member of the Executive Board Medical Director UKBB, Chief Physician Pediatrics, Member of the Executive Board, Research Group LeaderPediatrics, Emergencies0900 712 712(3.23 CHF/min. CH-landline, possibly likewise 8 Rp. / min. by network operator)0900 712 713(3.12 CHF/min. prepaid lamina phones, possibly likewise 8 Rp. / min. by network operator)Site Map ContactUniversity Children’s Hospital BaselSpitalstrasse 334056 Basel / SwitzerlandT +41 61 704 12 12F +41 61 704 12 13 Treatment & HospitalisationContact & Site MapAdmission & RegistrationDuring the HospitalisationDischargeFeedbackEmergency ResearchResearch at UKBBMajor Research TopicsResearch GroupsPromotion of Young ResearchersAmbulatory Study CenterResearch Networks MedicineMedical TopicsPhysicians & SpecialistsConsulting HoursParental DictionaryDownload Center CareerJob OffersWorking at the UKBBResidencyFurther Education The UKBBPhysicians & SpecialistsDepartments & ServicesMedical ExpertiseOrganisationNewsEventsMediaPro UKBB Foundation Contact & Site Map Legal RequirementsSite MapImprintPrivacy  EmergencyCallContactUniversity Children’s Hospital BaselSpitalstrasse 334056 Basel / SwitzerlandT +41 61 704 12 12F +41 61 704 12 13 Contact formSite MapImprintPrivacy © UKBB, 2018